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Xeomin is a "naked" botulinum toxin type A — stripped of accessory proteins present in Botox and Dysport. This pure formulation may reduce the risk of antibody resistance, making it a strong choice for long-term neurotoxin users.
Quick Answer
What is Xeomin?
Xeomin is a "naked" botulinum toxin type A — stripped of accessory proteins present in Botox and Dysport. This pure formulation may reduce the risk of antibody resistance, making it a strong choice for long-term neurotoxin users.
Avg. Cost
$250–$700 per treatment area
Duration
15–30 minutes
Downtime
None
Results
3–7 days onset, lasts 3–6 months
How Xeomin Works
Assessment & History Review
Your provider reviews your neurotoxin history (which products, how long, any reduced response) and assesses facial muscle activity to plan the optimal treatment.
Reconstitution
Xeomin requires refrigeration only after reconstitution. The powder is mixed with sterile saline to the provider's specified concentration.
Injection
Using a fine needle, small amounts of Xeomin are precisely injected into target muscles. The procedure takes 15-30 minutes.
Follow-Up
Results appear within 3-7 days. A 2-week follow-up allows for assessment and any needed touch-up.
Benefits of Xeomin
"Naked" formulation with no accessory proteins — may reduce antibody formation
Strong option for patients with reduced response to Botox after years of use
1:1 dosing ratio with Botox makes transitioning seamless
Potential for longer duration (up to 6 months) in some patients
FDA-approved with extensive global safety data
Xeomin Timeline & What to Expect
Day 1
Treatment administered — avoid rubbing and stay upright for 4 hours
Days 3-7
Results begin appearing as targeted muscles gradually relax
Week 2
Full effect visible; wrinkles smoothed with natural facial movement preserved
Month 3-4
Results maintained; some patients report longer duration than Botox
Month 4-6
Effects begin to fade; schedule next session to maintain results
Am I a Good Candidate for Xeomin?
Good Candidate
- ✓Long-term Botox users who notice faster-wearing-off results
- ✓Patients who prefer a pure formulation with no additives
- ✓Adults with forehead lines, frown lines, or crow's feet
- ✓Those switching from Botox seeking a fresh start with a different product
May Not Be Ideal
- ✗Pregnant or breastfeeding women
- ✗Patients with neuromuscular disorders
- ✗First-time neurotoxin patients without a specific reason to choose Xeomin over Botox
Xeomin Cost Breakdown
| Item | Typical Cost |
|---|---|
| Frown lines (glabella) | $150–$350 |
| Forehead lines | $100–$250 |
| Crow's feet (per side) | $80–$180 |
| Full upper face | $300–$700 |
* Costs vary by provider, location, and treatment area. Contact providers directly for exact pricing.
Financing Available for Xeomin
Many providers offer flexible payment plans through CareCredit, Cherry, and other financing options. Estimated from $21/month with 0% APR financing.
Financing availability varies by provider. Monthly payment estimates are approximate and based on 12-month terms. Contact your chosen provider for exact rates and terms.
Xeomin vs. Alternatives
| Treatment | Key Difference |
|---|---|
| XeominCurrent | $250–$700 per treatment area · 15–30 minutes · None |
| Botox | Botox (onabotulinumtoxinA) contains accessory proteins that some long-term users develop antibodies to. Xeomin's pure formulation may maintain effectiveness longer for these patients. |
| Dysport | Dysport spreads more widely and activates faster. Xeomin is more localized like Botox. Both are alternatives if Botox loses effectiveness over time. |
Top Xeomin Providers

Lov MedSpa Staten Island
Staten Island, NY

Lov MedSpa West Farms
Farmington, CT

Vesper
Chicago, IL

Pureaty Aesthetics
Las Vegas, Nevada
Injectologie
Coral Gables,
More cities with xeomin providers
Frequently Asked Questions about Xeomin
What makes Xeomin different from Botox?
Xeomin (incobotulinumtoxinA) contains only the pure botulinum toxin molecule without the accessory proteins in Botox and Dysport. This "naked" formulation may reduce the chance of developing antibodies that make the toxin less effective over time.
Does Xeomin last longer than Botox?
Some clinical studies report Xeomin lasting 3-6 months — potentially longer than Botox's average of 3-4 months. Individual results vary based on metabolism and muscle activity.
Who should choose Xeomin over Botox?
Xeomin is particularly beneficial for patients who have used Botox for many years and notice it wearing off faster — a sign of potential antibody formation. Switching to Xeomin's pure formulation may restore full effectiveness.
How is the Xeomin dosage different?
Xeomin uses a 1:1 unit ratio with Botox — the same number of units provides equivalent results, making it straightforward to transition between the two without dose adjustments.
Is Xeomin FDA-approved?
Yes — Xeomin is FDA-approved for glabellar lines (frown lines between the brows) and has been used safely in over 84 countries for both cosmetic and therapeutic applications.
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